You can Use Custom Per Page Widget Areas to create your own custom widget layout, and display them on your page with the "Plus" widget_area shortcode using any of the existing style and layout options available in the Theme, as shown on the Shortcode > Plus Plugin page.

You can also code them yourself using the tutorial found here: Columns and Widgets Tutorial.
Or in some cases, you may have your own custom widget layout (here made with this Code Generator).
In these cases, you may want to be able to use one of the nice advanced feature of "Plus" which is the Widget Height Equalization.

Xtreme lets you do just that using the method described in Item 2 of this Tutorial.

Resize your browser to observe equalization through changes of layouts.

Widget 1
Widget 2 Widget 2 Widget 2 Widget 2
Widget 3 Widget 3 Widget 3 Widget 3 Widget 3 Widget 3 Widget 3 Widget 3 Widget 3 Widget 3 Widget 3
Widget 4 Widget 4 Widget 4
Widget 5 Widget 5 Widget 5
Widget 6 Widget 6
Widget 7 Widget 7 Widget 7 Widget 7 Widget 7
Widget 8 Widget 8 Widget 8
Widget 9 Widget 9 Widget 9 Widget 9 Widget 9
Widget 10 Widget 10 Widget 10 Widget 10 Widget 10
Widget 11 Widget 11 Widget 11 Widget 11 Widget 11 Widget 11 Widget 11 Widget 11 Widget 11 Widget 11 Widget 11
Widget 1
Widget 2 Widget 2 Widget 2 Widget 2
Widget 3 Widget 3 Widget 3 Widget 3 Widget 3 Widget 3 Widget 3 Widget 3 Widget 3 Widget 3 Widget 3
Widget 4 Widget 4 Widget 4
Widget 5 Widget 5 Widget 5
Widget 6 Widget 6
Widget 7 Widget 7 Widget 7 Widget 7 Widget 7
Widget 8 Widget 8 Widget 8
Widget 9 Widget 9 Widget 9 Widget 9 Widget 9
Widget 10 Widget 10 Widget 10 Widget 10 Widget 10
Widget 11 Widget 11 Widget 11 Widget 11 Widget 11 Widget 11 Widget 11 Widget 11 Widget 11 Widget 11 Widget 11